Study Drug Details
Parkinson’s disease is a brain disorder that gets worse over time. It can cause shaking, stiff muscles, and slow or unsteady movements. It can also affect sleep and memory.
New research shows that swelling (inflammation) in the brain plays an important role in how Parkinson’s disease starts and gets worse. Some genes linked to a process called the JAK-STAT pathway have been connected to Parkinson’s disease. Scientists think that stopping this pathway might help slow the disease.
People with Parkinson’s disease often have high levels of inflammation in their brains and bodies. This inflammation can lead to damage and problems with how the body works. In lab animals, medicines that block the JAK-STAT pathway have helped reduce this damage.
BHV-8000 is a new medicine being studied for Parkinson’s disease. It works by blocking the JAK-STAT pathway to lower inflammation. This may help slow down how fast Parkinson’s disease gets worse.
Study Details
SCREENING PHASE
There will be a Screening Phase lasting up to 8 weeks. Because of the procedures required, there could be multiple visits needed to complete all screening tests and procedures.
DOUBLE-BLIND STUDY PHASE
This phase is 48 weeks long with the Baseline Visit and 9 study visits.
FOLLOW-UP PHASE
This phase is 4 weeks long with 1 study visit scheduled 4 weeks after your last visit in the double-blind phase.
There may be visits which the study doctor schedules, in addition to those above.